Home > Case Analysis & Patient Stories > Motor Neuron Disease
The patient stories published here are all those subject to the patient's consent.
| Amyotrophic Lateral Sclerosis | Ankylosing Spondylitis | Anti-aging | Ataxia | Autism | Batten Disease | Brain Injury | Cerebral Palsy | Charcot-Marie-Tooth | Chorea | Chronic-Inflammatory-Demyelinating-Polyneuropathy | CIDP | Dementia | Diabetes | Dystonia | Encephalitis/Myelitis Sequela | Encephalomyelitis | Epilepsy | Eye Disorder | Huntington's Disease | Lumbar Plexus Nerve Injuries | Motor Neuron Disease | Moyamoya Disease | Multiple Sclerosis | Multiple System Atrophy | Muscular Diseases | Myasthenia Gravis | Osteogenisis Imperfecta | Others | Parkinson Disease | Periventricular Leukomalacia | Polymyositis | Progressive Bulbar Palsy | Progressive Supranuclear Paralysis | Renal Insufficiency | Rheumatoid Arthritis | Spinal Cord Injury | Spinal Muscular Atrophy | Stroke | Systemic lupus erythematosus | Systemic Sclerosis | Ulcerative Colitis | West Syndrome |

Case Analysis : Case Analysis for Motor Neuron Disease

Case Analysis for Motor Neuron Disease
By Bo Cheng,Like Wu, Xiaojuan Wang and Susan Chu
Wu Medical Center

The motor neuron diseases (MNDs) are a group of progressive neurological disorders that destroy motor neurons, the cells that control essential voluntary muscle activity such as speaking, walking, breathing, and swallowing. Normally, messages from nerve cells in the brain (called upper motor neurons) are transmitted to nerve cells in the brain stem and spinal cord (called lower motor neurons) and from them to particular muscles. Upper motor neurons direct the lower motor neurons to produce movements such as walking or chewing. Lower motor neurons control movement in the arms, legs, chest, face, throat, and tongue. Spinal motor neurons are also called anterior horn cells. Upper motor neurons are also called corticospinal neurons.

When there are disruptions in the signals between the lowest motor neurons and the muscle, the muscles do not work properly; the muscles gradually weaken and may begin wasting away and develop uncontrollable twitching. When there are disruptions in the signals between the upper motor neurons and the lower motor neurons, the limb muscles develop stiffness, movements become slow and effortful, and tendon reflexes such as knee and ankle jerks become overactive. Over time, the ability to control voluntary movement can be lost.

Although there are now gene test for some MNDs there are no specific tests to diagnose most MNDs. Symptoms may vary among individuals and, in the early stages of the disease. MNDs may be similar to those of other diseases, making diagnosis difficult. A physical exam is followed by a thorough neurological exam. The neurological exam is to assess motor and sensory skills, nerve function, hearing and speech, vision, coordination and balance, mental status, and changes in mood or behavior.
There is no cure or standard treatment for the MNDs. Symptomatic and supportive treatment can help people be more comfortable while maintaining their quality of life.

Case Presentation
Carol Bell came to Wu Medical Center with a history of motor neuron disease which was diagnosed in another hospital. She presented with abnormal sensation in her lower limbs, inability to walk and could barely communicate with her neighbors.
Based on the symptoms presented, physical examination which was corroborated with gene test, Carol Bell diagnosis was confirmed as one of the motor neuron diseases.

Carol Bell received the most advanced stem cells therapy in Wu Medical Center. Treatment included: neural stem cells (NSCs) located accurately; the cells differentiate into targeting cells. In this disease, we need NSCs to differentiate into motor neuron. Carol Bell was managed using stem cells therapy for 2 weeks. This was done under a strict medical procedure to prevent any complication that may arise and it was accompanied with intensive rehabilitation. The course of therapy was planed and guided by experienced senior physician. This rehabilitation was done by a physiotherapist.

After two weeks of treatment, patient is able to communicate and write. Her motor function and exercise tolerance have improved. She can walk with little aid. This means that there has been an improvement in muscle power of both upper and lower limbs. Sensation has also returned. She able to undertake basic activities and quality of life has generally improved.

Though there is no cure for MNDs, Stem cells therapy can stop the disease getting worse, fix some nerve functions, help people be more comfortable while maintaining their quality of life

Patient Stories:

Name : Israr Ud Din Sex : Male Nationality : Pakistani Age : 45Y Diagnosis : Motor neural disease Date of Admission : March 3th, 2017 Treatment hospital/period : Wu Medical Center/14 days Before treatment : The patient felt weakness in his left hand

Posted at 2017-09-06 by Zhangqi views(0)

Name : Ms. Salmen Sex : Female Nationality : Pakistani Age : 38Y Diagnosis : 1. MND 2. Post Gastrostomy Date of Admission : April 13th, 2017 Treatment hospital/period : Wu Medical Center/14 days Before treatment: 3 years ago the patient had no obvi

Posted at 2017-08-18 by Zhangqi views(4)

Name : I Gede Sanjaya Dinata Kusuma Sex : Male Nationality : Indonesian Age : 52Y Diagnoses : 1.Motor Neuron Disease 2.Sinus Bradycardia 3. Hypothyroidism Date of Admission: November 12th, 2016 Treatment hospital/period : Wu Medical Center/15days Be

Posted at 2017-03-30 by Zhangqi views(34)

Name: Peter Atkins Sex: Male Nationality: British Age: 73 Diagnoses: 1. Motor Neuron Disease: Amyotrophic Lateral Sclerosis 2. Coronary Artery Stenosis(Coronary Artery Bypass) 3. Level I A-V block 4. Artbrolithiasis Date of Admission: May 16, 2016 Tr

Posted at 2016-08-16 by Zhangqi views(64)

Name: Michal Luczak Sex: Male Nationality: Polish Age: 29 Diagnosis: Amyotrophic Lateral Sclerosis (ALS) Date of Admission: Mar.27, 2016 Treatment hospital/period: Wu Medical Center/17 days Before treatment: Michal felt weakness in his right hand a

Posted at 2016-05-16 by Zhangqi views(77)

Name: Thomas Sex: Male Nationality: French Age: 57 Years Diagnosis: 1. Amyotrophic Lateral Sclerosis(ALS) 2. Hyperlipemia Date of Admission: Jan.14, 2016 Treatment hospital/period: Wu Medical Center/17 days Before treatment: The patient went to hos

Posted at 2016-02-19 by Zhangqi views(118)

Name: Blair Kurtz Sex: Male Country: Australia Age: 52 years Diagnosis: 1. Motor Neuron Disease/ Amyotrophic Lateral Sclerosis 2. Sinus bradycardia3. Hyperlipemia Date of Admission: November 5th, 2015 Treatment Hospital/period :Wu Medical Center/13 d

Posted at 2015-12-10 by Zhangqi views(121)

Name: Martin Henderson Sex: Male Nationality: England Age: 60 Years Diagnosis: 1. Motor Neuron Disease 2. Hyperlipidemia 3. Arrhythmias Complete Right Bundle Branch Block I level Heart Function Date of Admission: Aug. 19, 2015 Treatment hospital/peri

Posted at 2015-09-18 by Zhangqi views(144)
Tel: +86-10-83614932 Fax: +86-10-83614167 Email:  inquiry@wumedicalcenter.com   Contact Us 
Copyright@2013 Runde Healthcare Consulting Limited.