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Author Admin Views Posted at 2013/04/23

by Drs.Like Wu, Xiaojuan Wang and Bo Cheng

Through long-term practice, people identify the disease whose characteristics are  myelinolysis in the brain and spinal cord to demyelinating disease of the central nervous system. MS is the most common type, which can represent a demyelinating disease.

Nosogenesis: MS is related to virus infection and Post-infectious autoimmune mechanism.

1. Multiple Sclerosis
   A. chronic recurrent cerebral spinal cord sclerosis.
   B. Acute multiple sclerosis
   C. Schilder's diffuse cerebral sclerosis and Balo concentric diffuse cerebral sclerosis.
2. Optic nerve myelin inflammation (Devic's disease).
3. Acute disseminated encephalomyelitis: after hives, crystalli infection or after some vaccine inoculation.
4. Acute and sub-acute necrotizing hemorrhagic encephalitis.


1. Medullated nerve fiber damage.
2. Other Neural tissue components remain.
3. Blood vessels in the corresponding area have acute inflammation of the effusion.
4. The characteristic lesion distribution.
5. Few Wallerian degeneration or secondary fiber bundle degeneration.

MS can represent this kind of disease, because it has high incidence rate, chronic course, susceptible adolescents, MS is one of the most major nervous system disease.

Disease characteristics: invades central nervous system certain parts, causes severe fatigue and some complex symptoms and signs and change of radiological images which are easily recognizable.

Clinical manifestation:

Include: Motor weakness, limb paresis or paralysis, abnormal sensation, visual impairment, diplopia, nystagmus, ataxia and bladder dysfunction (urinary incontinence) and so on.

Laboratory examination abnormal item: cytology of cerebrospinal fluid, protein. Radiographic: abnormal T2 magnetic resonance signal around encephalocoele, multiple scattered lesions. About half of patients show intermittent progress, some patients have continuing progress (durative accentuation).

The clinical course and prognosis: recurrent attacks, exacerbations in a series of attacks, every time attack occurs the remission period is shortened, these are important clinical attributes of MS.

Some patients show a series of relapses, this kind of relapse may cause paralysis of limbs and bulbar paralysis cause breathing and swallowing difficulty.

Pathologic process have long time potential motility.

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