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Case Analysis : Case Analysis for Autism

Case Analysis for Charcot-Marie-Tooth Disease(May 25th, 2015)
Like Wu, Xiaojuan Wang, Freda Peng, Bo Cheng, Susan Chu
Wu Medical Center(2015-5-25)

The patient is 8-year-old boy. He was presented with language, mental, behavioral and human communication disorders for the past 5 years. He was diagnosed as Autism. He was born full-term with normal delivery. He was hyperactive, upset, agitated, impaired language development and was unable to communicate with others when he was 2 years old.

Physical examination: he was stable, Skin and mucous membrane were with no yellow stain or petechia. His heart and lung were normal. He was alert, his comprehension, judgment, attention and adaptability were bad. He was hyperactive, upset, unquiet, soliloquize and he couldn’t answer questions. He could count from 1-10. He couldn’t cooperate with the memory, calculation ability, or orientation examinations. He seldom had eye contact with others. He couldn’t cooperate with the cranial nerves, sensation and coordinated movement during examinations. The muscle power of four limbs was at level 5, his muscle tension was normal. The tendon reflex decreased. The pathological sign was negative. All of the laboratory examination and accessory examinations were normal. He was diagnosed as” Autism”.

Treatment target: increase the number of normal neural stem cells (NSCs) in the brain, switch on neural development, repair and regenerate the nerves. Increase the brain function, improve the patient’s cognitive function and communication skills.

Treatment procedure and results:
We gave the patient 4 times neural stem cells (NSCs) and 4 times mesenchymal stem cells (MSCs) implantation treatment. The stem cells were activated in the patient’s body to repair the damaged nerves. Together with nourishment of the neurons, improve circulation, regulating the immune, daily rehabilitation training was incorporated. After the treatment, the patient was stable, developed a good spirit and mood. He seldom gets upset and he developed more concentration. He could see movies or listen to music by himself, and the duration was increased to between 30-40 minutes than before. He speaks more with family members. He could answer questions and gained more vocabulary. He could say a sentence which is made up of 6 words. His learning skill was better. The memory, calculation ability, orientation, comprehension and attention were better. He had more eye contact with others. His nerves, sensation, coordinated movement examinations and meningeal irritation sign examination cooperation degree was better.

Case analysis:
Autism is also called autistic disorder, it is one subtype of the catholicity eccyliosis. Male patients were more than female as observed. This disease onset at early infancy. The cardinal symptoms: various degrees of speech disturbance, human communication disorders, less interesting or mechanic behavior. Around 3/4 young patients accompanied with visible mental retardation. The main pathogen was unclear, it may be: heredity, perinatal period factors, abnormal immune system or imbalance of various neuroendocrine and neurotransmitter function. The patient had this disease from very young, the pathogen was unclear, and his symptoms were: abnormal mind and behaviors, cognitive disorder, bad communication skills and excitement.

There are a lot of methods to treat autism, but most of them lack medical evidences and there is no best treatment plan. Our center uses advanced NSCs transplantation technique to treats patients with autism. The NSCs is used together with MSCs to make the imbedded NSCs increase the number of brain and spinal cord nerve cells, promotes nerve differentiation and growth to improve his cognition and mental. This technique was used in this patient and he recovered well and not only his cognition and mental, his self-care ability and social skills were improved also. This provided relief of mental stress and daily burden to his relatives. This brings hope to patients with this disease.

Research under our direction, the treatment result was satisfactory. During retrospective experiment on animals, we found the same program had made great advances in nerve precursor cell’s structure, migration, cortical tissue, neuron differentiation and connection. For example: a small group of neurons migration lag in specific area or appear in ectopia area of the patient, could result in mental hypoevolutism, epilepsy or speech impediment. This can be fixed with implantation of nerve precursor cell. The shape and structure of cortex can be normal. The safety of this treatment was confirmed in many medical literatures. But each patient need complicated clinical technology supporting, because the brain was controlled by gene in the development process, for example: when we use the NSCs to correct neuron developmental deviation and abnormality, neuron development need growth factors’ participation. It also need immunological surveillance. Over growth nerve will be controlled by immune system, only in that way can we get good result. All the processes need to be controlled by experienced clinician and complicated clinical technology.

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Patient Stories:

Case Analysis : Autism

by Drs. Like Wu, Xiaojuan Wang and Bo Cheng

Autism is a disorder of neural development characterized by impaired social interaction and verbal and non-verbal communication, and by restricted, repetitive or stereotyped behavior. The diagnostic criteria require that symptoms become apparent before a child is three years old. Autism affects information processing in the brain by altering how nerve cells and their synapses connect and organize; it is unknown how this occurs. It is one of three recognized disorders in the autism spectrum (ASDs), the other two being Asperger syndrome, which lacks delay in cognitive development and language, and pervasive developmental disorder, not otherwise specified (commonly abbreviated as PDD-NOS), which is the diagnosis when the full set of criteria for autism or Asperger syndrome are not met.

Parents usually notice signs in the first two years of their child's life. The signs usually develop gradually, but some autistic children first begin to develop normally and then regress. Early behavioral, cognitive, or speech interventions can help autistic children gain self-care, social, and communication skills. Not many children with autism live independently after reaching adulthood, though some become successful. An autistic culture has developed, with some individuals seeking a cure and others believing autism should be accepted as a difference and not treated as a disorder.

Autism is a highly variable neurodevelopmental disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Overt symptoms gradually begin after the age of six months, become established by the age of two or three, and tend to continue through adulthood, although often in a more muted form. It is distinguished not by a single symptom, but by a characteristic triad of symptoms: impairments in social interaction; impairments in communication; and restricted interests and repetitive behavior. Other aspects, such as atypical eating, are also common but are not essential for diagnosis.

Autism's individual symptoms occur in the general population and appear not to be highly related, and it lacks a clear line separating pathologically severe from common traits.

There is no specific drug to treat autism. Special education and training curriculum system can improve prognosis. With the increased study of autism, we have gradually realized that autism is a diffuse developmental disorder of the central nervous system, which falls under certain genetic factors, and is caused by the stimulation of various kinds of environmental factors. All kinds of genetic factors and environmental factors interfere with the normal development of the nervous system. The patient may have less normally functional nerve cells in the brain than other children of the same age. There has been significant stagnation in growth in many encephalic regions. After many years of study, the Wu Stem Cell Medical Center (WSCMC) found that restarting the nervous system development of the brain is important to treat autism. The WSCMC used neural stem cell implants, in addition to unique stem cell regulation techniques for the body, in order to enable the implanted neural stem cells to reach the target organs and restart the development of specific nerve cells in the brain. This can significantly improve the symptoms of autism, and improve the environmental communication skills and self-care ability required in daily life.

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Patient Stories:

Name : Abbas Habib Sex : Male Nationality : Pakistani Age : 20Y Diagnosis : Autism Date of Admission : July 16th, 2017 Treatment hospital/period : Wu Medical Center/14days Before treatment: Abbas was a full-term normal delivery baby, the doctor use

Posted at 2017-11-01 by Zhangqi views(0)

Name : Joanna Kristina Olivia Sex : Female Nationality : Indonesian Age : 13Y Diagnosis : Autism Date of Admission : April 11th, 2017 Treatment hospital/period: Wu Medical Center/12 days Before treatment: The patient was found to have language deve

Posted at 2017-10-10 by Zhangqi views(1)

Name: Endel Rodriguez Sex: Male Nationality: Puerto Ricans Age: 9 Diagnoses: 1. Autism 2. Aphasia Date of Admission: July 18th, 2016 Treatment hospital/period: Wu Medical Center/15days Before treatment: When Endel was 1 and half years old, his pare

Posted at 2016-09-13 by Zhangqi views(58)

Name: Martin Sex: Male Nationality: British Age: 6 Diagnosis: Autism Date of Admission: April 11, 2016 Treatment hospital/period: Wu Medical Center/20 days Before treatment: Martins sucking function was bad when he was born, so his parents took him

Posted at 2016-08-19 by Zhangqi views(41)

Name: Alan Sex: Male Nationality : British Age: 6 Years Diagnosis: 1. Autism 2. Epilepsy Date of Admission: Feb.19, 2016 Treatment hospital/period : Wu Medical Center/14 days Before treatment: Alan was normal when he was born, but he began to have

Posted at 2016-03-30 by Zhangqi views(125)

Name: Leo Sex: Male Nationality: Australian Age: 5 Years Diagnosis: Autism Date of Admission: Feb.16, 2016 Treatment hospital/period: Wu Medical Center/14 days Before treatment: Leo was hyperactive at the age of 1.He developed his speaking ability l

Posted at 2016-03-29 by Zhangqi views(125)

Name: Ausand Jermi Sex: Male Country: Pakistan Age:17 years Diagnosis:Autism Date:July 21, 2014 Days Admitted to Hospital: 21 days Before treatment: The patient suffered fromlanguagedeficit when he was 1 year and 6 months old. He had less communicati

Posted at 2014-08-18 by Admin views(296)

Name: Malachi Kenken Sex: Male Country: Papua New Guinea Age:9 years Diagnosis:Autism Date:July 21, 2014 Days Admitted to Hospital: 21 days Before treatment: He was born through a full-term normal delivery. There was no history of oxygen deficit duri

Posted at 2014-08-15 by Admin views(218)
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